Dermatophytes DP
The DendrisKIT DP is dedicated to the identification of 12 fungi involved in dermatophytosis.
CE IVD marking in May 2022
DendrisKIT DP
Dermatophytes
- Candida albicans
- Epidermophyton floccosum
- Microsporum spp.
- Nannizzia gypsea
- Trichophyton spp.
- Trichophyton benhamiae
- T. mentagrophytes/interdigitale
- Trichophyton rubrum
- Trichophyton soudanense
- Trichophyton tonsurans
- Trichophyton verrucosum
- Trichophyton violaceum
Dermatophytosis are mycotic infections of the skin, hair and nails caused by filamentous microscopic fungi belonging to the genera Candida, Trichophyton, Microsporum and Epidermophyton. These infections are very common in the population (about 22% in European countries). Mycological diagnosis by conventional culture takes several weeks, unlike the molecular biology test proposed by Dendris, which can detect all the pathogens responsible for dermatophytosis in a single analysis while providing a rapid result. The medical service rendered of our solution considerably reduces the time of detection and identification (24 hours compared to 3-4 weeks) and its sensitivity is 30% higher than the culture.
Dendris with its molecular biology kit, based on DNA microarray technology, offers results in about 5 hours to cover the 12 fungi most responsible for dermatophytosis.
The kit includes:
– all reagents and consumables needed for sample pre-treatment, 18S/ITS combined PCR and hybridization
Key features | Benefits | |
Simultaneous detection of 12 targets | Large panel of dermatophytes and yeasts in one test | Time saving |
Validated analysis from swabs | Directly from the patient | Simplified and fast sampling |
Results interpreted at D0 | Faster diagnosis than conventional methods | To improve patient care |
Automated process | Hybridization on automated platform | Robust analysis, security and productivity |
Easy to interpret | Results rendering software using machine learning (AI) methods | No expertise required |
High speed | 64 tests per run from primary sample | Adapted to technical platforms |
Validated | Passing of NEG and POS controls for each series | Secure rendering of results |
CE marking results
Dermatophytes
Number of samples mark
441 samples
Types of samples mark
Validated on swab of the infected area with dry swab
All types of human samples used in mycology
– Nails
– Hair
– Skin
Performance
Pathogens | Sens. (%) | Spe. (%) | VPN (%) | VPP (%) |
C. albicans | 100 | 99,5 | 96,0 | 100 |
E. floccosum | 100 | 100 | 100 | 100 |
Microsporum spp. | 97,8 | 100 | 100 | 99,7 |
N. gysea | 100 | 100 | 100 | 100 |
Trichophyton spp. | 88,4 | 98,9 | 99,1 | 86,6 |
T. benhamiae | 87,5 | 99,5 | 91,3 | 99,3 |
T. mentagrophytes /interdigitale | 92,2 | 99,2 | 95,2 | 98,7 |
T. rubrum | 100 | 99,2 | 93,9 | 100 |
T. soudanense | 82,8 | 100 | 100 | 98,8 |
T. tonsurans | 86,4 | 99,0 | 82,6 | 99,3 |
T. verrucosum | 90,0 | 99,8 | 96,4 | 99,3 |
T. violaceum | 92,0 | 100 | 100 | 99,5 |
Publications
Rapid and Accurate Diagnosis of Dermatophyte Infections Using the DendrisCHIP® Technology
Diagnostics 2023, 13 Novembre 2023